Noah Isakov is the Joseph H. Krupp Professor in Cancer Immunobiology at the Shraga Segal Department of Microbiology, Immunology and Genetics, the Goldman Medical School, Ben Gurion University of the Negev, in Beer Sheva, Israel. His major interest is in signal transduction mechanisms in normal and transformed cells, predominantly in the immune system. He was involved in the discovery and characterization of new signaling molecules in T lymphocytes and continues studying the intricate signaling pathways that regulate T lymphocyte functions and T lymphocyte-mediated immune responses.

Our research focuses on various aspects of signal transduction in cells in general, and in T lymphocytes in particular. Studying mechanisms by which specific effector molecules regulate T cell activation, proliferation and differentiation will enable the design of new therapeutic modalities for attenuating undesired inflammatory responses and inhibit the growth of leukemic T cells.