Center for Perioperative Organ Protection
Duke University Medical Center
USA
Dr. Ulloa studies the physiological mechanisms controlling the immune system and their pharmacological translation for the treatment of infectious and inflammatory disorders. In special, Dr Ulloa is interested on the physiological, cellular, and molecular mechanisms of Neuromodulation of the immune system and their clinical implications in sepsis. Dr Ulloa has served and chaired numerous international conferences, Editorial Boards and grant review committees. Dr Ulloa has received prestigious awards and funding from the Human Frontiers Organization, NATO, the National AHA, DOD, and NIH.
My current research focuses on the physiological and cellular mechanisms of vagal modulation of the immune system in experimental sepsis. From a cellular standpoint, we were pioneers reporting that the vagus nerve controls inflammation via inducible T regulatory lymphocytes. Our studies were recently confirmed by other investigators. During the last years, we have studied the regulation of immune cells by typical neurotransmitters such as acetylcholine, dopamine, and norepinephrine. One critical consideration in our studies is the translation these mechanisms into novel therapeutic and pharmacologic strategies for infectious and inflammatory disorders.
Email: ulloalu[AT]njms[DOT]rutgers[DOT]edu