x
Nutrition & Energy Balance
Arvind Goja

Dept. of Pharmacology

University of Illinois at Chicago

USA

Journal Short Name - NEB

Biography

Accomplished, eager and motivated post-doctoral research associate holding a PhD with more than ten years of experience conducting high-level research in the area of potential biomarkers for aggressive diseases like lung cancer, pancreatic cancer and Alzheimer’s and in pre-ecalmpsia, hemodialysis patients.Well-versed in current techniques and softwares (NMR ACD, Multivariate Data Analysis tool SIMCA P+ 13.02, Metabolite Identification Software Chenomx) and cell culture. Successful collaborations with domestic and international research labs. Dedicated scholar with strong teaching experience and strategic approach to problem solving. Innovative and resourceful with excellent management and interpersonal skills, highly developed work ethic, and reputation for integrity.

Reasearch Interest

I finished my PhD with Department of Nutrition and Food Science (Diet, cancer and metabolomics) from Wayne State University, Detroit, MI in 2011. After finishing my PhD I was hired as Research Assistant and Part-time faculty with department of Nutrition food Science, WSU, Detroit, MI. During my Graduate years and as WSU employee I had an opportunity to work with various projects besides my own PhD Dissertation which helped me acquire required skills to run a lab as manager and researcher as well. My Dissertation project involved using metabolomics as a technique to evaluate effects of curcumin (nutraceutical) in lung cancer induced hamster animal model and to discover early potential biomarkers for lung cancer. I am well versed with molecular biology techniques (Gel electrophoresis, Comet assay, Protein assays, Gene expressions techniques), animal handling, animal blood draw and dissection, cell culture Techniques, Nuclear magnetic techniques (sample preparation, data acquisition and Interpretation) and software for multivariate data analysis (SIMCA P+) and Metabolite identification Software (Chenomx). I also had an opportunity to teach independently various undergraduate and graduate courses as teaching assistant and part-time faculty from year 2006-2014 at Wayne State University. The teaching responsibilities included designing the syllabus, setting up the exams, quizzes, assignments and field trips. I have had an opportunity to guide and motivate numerous undergraduate and graduate students in their research projects. My current job profile involves research and managing toxicology lab at university of Illinois, Chicago. My research involves conducting, and planning experiments to evaluate effect of anti-cancer drugs in in-vivo and in-vitro models pre and post exposure to irradiation (gamma radiations). These drugs have been formulated and developed by our group at University of Illinois (Chicago) and our interest is to screen drugs as potential radiomitigators and/or radioprotectors. My current test model cell lines are A549, MCF-7, Immortalized Intestinal epithelial cells and Dermal Fibroblast cells and my work involves maintaining these cell lines for various drug sensitivity and toxicity assays pre and post irradiation at different irradiation doses. I routinely work with techniques such as MTT assay, Clonogenic assay, rtPCR, RNA isolation (from cells lines, blood and tissues) and all the work is done under GLP conditions. I have been working on various cell lines and animal models for past 10 years. My primary research interest has been to evaluate diet-gene interaction using metabolomics as one of the approaches. I believe that food (diet) is the cause and food (nutraceuticals) could be the cure (therapeutic/preventative) for most of the diseases. Metabolomics approach provides non-invasive platform to screen the potential early biomarkers for various disease conditions when compared to control (healthy). I believe, in future, metabolomic profiles (urinary, plasma, salivary etc) of an individual or group of individuals would be considered/consulted before administering drugs or any other therapy as it takes in account the minor variabilities in individual’s biochemical pathways and metabolism. I have had an opportunity to implement metaboloimc approach (NMR based) to build urinary and plasma metabolomics profiles for various diseases conditions. I have evaluated urine metabolomics profiles for Lung Cancer induced Golden Syrian Hamsters, Various Cell lines (cancerous and Immortalized), Panceatic cancer mice model, Alzheimer’s Disease rat models, Hypercholesterolemic rat model, Preeclamptic pregnant women and in human population with dietary intervention. I have been invited by Universiti Kebangsaan, Malaysia as Course Faculty for workshop entitled: Nutrition, Metabolomics and Bioinformatics at Universiti Kebangsaan, Malaysia. My role was to teach and train students, faculty and other participants regarding metabolomic approach, designing experiments, collection of samples, evaluation and interpretation of data using multivariate data analysis software (SIMCA P+).

Signup to recive email updatesx